Patent · US Expired

Methods of conferring ppo-inhibiting herbicide resistance to plants by gene manipulation

US7586023B1 · kind B1 · utility

2Cited by
3References
15Claims
0Family size

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Key dates

Filing dateDec 27, 1996
Grant dateSep 8, 2009
Priority date
Expiry dateDec 27, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/18
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The present invention provides methods to confer resistance to protoporphyrinogen-inhibiting herbicides onto crop plants. Resistance is conferred by genetically engineering the plants to express cloned DNA encoding a protoporphyrinogen oxidase resistant to porphyric herbicides. If such resistant crop plants are cultivated, utilization of these herbicides on fields of these crop plants becomes feasible. This should allow for simpler and more effective weed management, and increase the value of these herbicides for agricultural use. Furthermore, the present invention provides plants, algae, plant cells, and algal cells which have been made resistant to protoporphyrinogen oxidase-inhibiting herbicides by the subject methods using a herbicide-resistant protoporphyrinogen oxidase gene that has been prepared by genetic engineering methods. In addition, the present invention provides methods to evaluate the inhibitory effects of test compounds on protoporphyrinogen oxidase activity, as well as methods to identify protoporphyrinogen oxidase inhibitors among test compounds. Preferred cloned DNA fragments encoding protoporphyrinogen oxidase enzymes resistant to porphyric herbicides are also …

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.