Patent · US Expired

Methods for remodeling cardiac tissue

US7588582B2 · kind B2 · utility

310Cited by
160References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 20, 2005
Grant dateSep 15, 2009
Priority date
Expiry dateOct 20, 2025

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61F2/2445
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Described herein are methods of remodeling the base of a ventricle. In particular, methods of remodeling a valve annulus by forming a new fibrous annulus are described. These methods may result in a remodeled annulus that corrects valve leaflet function without substantially inhibiting the mobility of the leaflet. The methods of remodeling the base of the ventricle include the steps of securing a plurality of anchors to the valve annulus beneath one or more leaflets of the valve, constricting the valve annulus by cinching a tether connecting the anchors, and securing the anchors in the cinched conformation to allow the growth of fibrous tissue. The annulus may be cinched (e.g., while visualizing the annulus) so that the mobility of the valve leaflets is not significantly restricted. The remodeled annulus is typically constricted to shorten the diameter of the annulus to correct for valve dysfunction (e.g., regurgitation).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.