Eutectic-based self-nanoemulsified drug delivery system
US7588786B2 · kind B2 · utility
18Cited by
17References
13Claims
0Family size
Assignee
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Key dates
| Filing date | Nov 14, 2002 |
| Grant date | Sep 15, 2009 |
| Priority date | — |
| Expiry date | Nov 14, 2022 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/4858
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A eutectic-based self-nanoemulsified drug delivery system (SNEDDS) is formulated from polyoxyl 35 castor oil (Cremophor), medium chain mono- and diglycerides (capmul), essential oils, and a pharmacologically effective drug or nutraceutical or dietary supplement. The preferred pharmacologically effective drug is a poorly water soluble drug, such as ubiquinone (CoQ10). The SNEDDS can be further incorporated into a powder to produce a solid dosage form. The solid dosage form contains the SNEDDS, a copolymer of vinylpyrrolidone and vinyl acetate (Kollidon VA 64), maltodextrin, and microcrystalline cellulose (MCC).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.