Surface modification for improving biocompatibility
US7589070B2 · kind B2 · utility
2Cited by
6References
55Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 14, 2002 |
| Grant date | Sep 15, 2009 |
| Priority date | — |
| Expiry date | Apr 18, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A therapeutic delivery system efficiently introduces biologically active molecules to mammalian cells without the use of synthetic polymers or biopolymer coatings. Surface modification of a metal support, such as a medical device, results in a single molecular layer that can fasten various molecules, thereby minimizing any cellular inflammatory response while enhancing biocompatibility.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.