System and method for detecting hypoglycemia based on a paced depolarization integral using an implantable medical device
US7590443B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Apr 27, 2005 |
| Grant date | Sep 15, 2009 |
| Priority date | — |
| Expiry date | Dec 27, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2205/3523
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Techniques are provided for use with an implantable medical device such as a pacemaker or implantable cardioverter/defibrillator (ICD) for predicting and detecting hypoglycemia. In one example, the device tracks changes in a paced depolarization integral (PDI). A significant increase in PDI over a relatively short period of time indicates the onset of hypoglycemia (this can also be confirmed with QT changes). Upon detection of hypoglycemia, appropriate warning signals are generated to alert the patient. Certain therapies automatically provided by the implantable device may also be controlled in response to hypoglycemia. For example, if the patient is an insulin-dependent diabetic and the implantable device is equipped with an insulin pump capable of delivering insulin directly into the bloodstream, insulin delivery is automatically suspended until blood glucose levels return to acceptable levels. If the device is an ICD, it may be controlled to begin charging defibrillation capacitors upon detection of hypoglycemia so as to permit prompt delivery of a defibrillation shock, which may be needed if hypoglycemia triggers ventricular fibrillation. The detection techniques may be used in…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.