Methods for determining hepatotoxins
US7590493B2 · kind B2 · utility
16Cited by
12References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 17, 2005 |
| Grant date | Sep 15, 2009 |
| Priority date | — |
| Expiry date | Jun 16, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/5067
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is based on the elucidation of the global changes in gene expression and the identification of toxicity markers in tissues or cells exposed to a known toxin. The genes may be used as toxicity markers in drug screening and toxicity assays. The invention includes a database of genes characterized by toxin-induced differential expression that is designed for use with microarrays and other solid-phase probes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.