Macrocyclic inhibitors of hepatitis C virus NS3-serine protease
US7592419B2 · kind B2 · utility
10Cited by
1References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 23, 2004 |
| Grant date | Sep 22, 2009 |
| Priority date | — |
| Expiry date | Jan 13, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0802
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses novel compounds which have HCV protease inhibitory activity as well as pharmaceutical compositions comprising such compounds and methods of using them to treat disorders associated with the HCV protease. The novel compounds typically include a 15-20 member macrocycle and have the general structure of structural Formula 1:wherein Z′, L′, M′, R1, X and D are defined herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.