Knock-in non-human animal producing human tissue factor
US7592502B2 · kind B2 · utility
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Key dates
| Filing date | May 17, 2002 |
| Grant date | Sep 22, 2009 |
| Priority date | — |
| Expiry date | Apr 23, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A non-human animal that produces human tissue factor (TF) without substantially producing non-human animal tissue factor, said animal having a genome in which cDNA encoding human TF has been inserted upstream of the translation initiation codon for the non-human animal genomic TF gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.