Method of detecting a neoplasia associated with an activating platelet derived growth factor receptor alpha (PDGFRA) mutation
US7595154B2 · kind B2 · utility
2Cited by
7References
44Claims
0Family size
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Key dates
| Filing date | Jun 13, 2003 |
| Grant date | Sep 29, 2009 |
| Priority date | — |
| Expiry date | Nov 29, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This disclosure provides tyrosine kinase protein and nucleic acid variants, particularly PDGFRA variants, which are activating forms of these molecules and are linked to neoplasms and/or the development or progression of cancer. The disclosure further provides methods of diagnosis and prognosis, and development of new therapeutic agents using these molecules and fragments thereof, and kits for employing these methods and compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.