Pyrrole derivatives

US7598274B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Dirk Finsinger · Darmstadt, DE
• Hans-Peter Buchstaller · Griesheim, DE
• Lars Burgdorf · Frankfurt am Main, DE
• Matthias Wiesner · Seeheim-Jugenheim, DE
• Christiane Amendt · Mühltal, DE
• Matthias Grell · Darmstadt, DE
• Christian Sirrenberg · Darmstadt, DE
• Frank Zenke · Darmstadt, DE

Key dates

• Filing date: Oct 26, 2004
• Grant date: Oct 6, 2009
• Expiry date: Feb 3, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula (I), in which X, Y, Z and Ar have the meanings indicated in claim 1, are inhibitors of Raf kinase and can be employed, inter alia, for the treatment of tumours