Folate-receptor-targeting iron oxide nanoparticles coated with poly(ethylene glycol)
US7598335B2 · kind B2 · utility
6Cited by
0References
10Claims
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Key dates
| Filing date | Jun 29, 2007 |
| Grant date | Oct 6, 2009 |
| Priority date | — |
| Expiry date | Oct 15, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/3344
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
The present invention provides the synthetic method and superparamagnetic iron oxide nanoparticles capable of targeting to the folic acid receptors existing on the cell membranes and with high relaxivity. The iron oxide nanoparticles of the present invention can further be used as the contrast agents for magnetic resonance imaging (MRI).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.