Method for the production of 4-(4-aminophenyl)-3-morpholinone

US7598378B2 · kind B2 · utility

Assignee

• Bayer Schering Pharma AG · DE

Inventors

• Christian Thomas · Wuppertal, DE
• Mathias Berwe · Sprockhövel, DE
• Alexander Straub · Wuppertal, DE

Key dates

• Filing date: Sep 9, 2004
• Grant date: Oct 6, 2009
• Expiry date: Jun 30, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to a process for preparing 4-(4-aminophenyl)-3-morpholinone by reacting 4-(4-nitrophenyl)-3-morpholinone with hydrogen in the presence of a hydrogenation catalyst, characterized in that the reaction is effected in an aliphatic alcohol.