Patent · US Active

Methods for the synthesis of unsymmetrical cycloalkyl substituted xanthines

US7598379B2 · kind B2 · utility

7Cited by
4References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 27, 2006
Grant dateOct 6, 2009
Priority date
Expiry dateMay 29, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides processes for making pyridyl-linked-xanthines of formula VII, from 5,6-diamino-1H-pyrimidine-2,4-diones of formula II and acylating agents of formula VI.The xanthines are expected to be are selective antagonists of A2B adenosine receptors (ARs).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.