Materials for the delivery of biologically-active material to cells
US7598421B2 · kind B2 · utility
7Cited by
7References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 8, 2004 |
| Grant date | Oct 6, 2009 |
| Priority date | — |
| Expiry date | Aug 21, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a lipid of general formula (I) or (II):wherein X1, X2 and R1 to R5 are as defined herein. Such lipids are used to form complexes with a biologically-active material such as a nucleic acid, peptide or small molecule for delivering the biologically-active material to cells. The complexes may incorporate an integrin-binding peptide and, when the biologically-active material is DNA, thereby constitute a LID complex.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.