Bioamplification for microbial sensor signal transduction

US7604953B2 · kind B2 · utility

Assignees

• IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. · US
• The United States of America as represented by the Department of Agriculture/Cooperative State Research Education and Extension Service (USDA/CSREES) · US

Inventors

• Marc D. Porter · Ames, US
• Betsy Jean Yakes · Alexandria, US
• Robert J. Lipert · Ames, US
• John P. Bannantine · Ames, US

Key dates

• Filing date: May 30, 2008
• Grant date: Oct 20, 2009
• Expiry date: May 30, 2028

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/35
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A process of detection of the causative agent of Johne's disease (Mycobacterium avium subsp. paratuberculosis) (MAP) by detecting shedding of surface protein of MAP. A preferred way is use of surface enhanced Raman Spectroscopy. The system of detecting MAP shedding of protein provides early detection and diagnosis, and therefore allows early treatment for Johne's disease in ruminant animals.