Excitable target marker detection

US7604981B1 · kind B1 · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• James S. Harris, Jr. · Stanford, US
• Stephen J. Smith · Los Gatos, US
• Evan Thrush · San Anselmo, US
• Ofer Levi · Los Altos, US

Key dates

• Filing date: Mar 7, 2003
• Grant date: Oct 20, 2009
• Expiry date: Jul 5, 2026

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N21/6408
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A variety of types of molecules are detected and/or analyzed using an integrated micro-circuit arrangement. According to an example embodiment of the present invention, a micro-circuit arrangement detects excitable target markers in response to an excitation source. The excitation source emits a first electromagnetic radiation to excite one or more target markers into emitting a second electromagnetic radiation. The excitation source and detector combination can be optimized to detect a specific characteristic of a biological specimen. In this manner, an excitation source can be combined with several optical-detectors or detection channels, where each optical-detector is measuring or sensing the same or different characteristic of the biological specimen.