DNA cancer vaccines
US7605139B2 · kind B2 · utility
2Cited by
1References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 2005 |
| Grant date | Oct 20, 2009 |
| Priority date | — |
| Expiry date | Oct 21, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/7072
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A plurality of DNA cancer vaccines and their uses in treating cancer are disclosed. Genes encoding Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG) recombinant antigens and genes encoding interleukin-12 heterodimer were respectively cloned into eukaryotic expression vectors to express the encoded recombinant proteins in mammalian cells in vivo whereby specific immune responses are evoked and are effective in preventing, attenuating and/or suppressing the growth of a tumor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.