Modulation of the phospholipase A2 pathway as a therapeutic
US7605149B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 13, 1999 |
| Grant date | Oct 20, 2009 |
| Priority date | — |
| Expiry date | Jul 13, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is provided a method of modifying vasoactivity by regulating a soluble Aβ pro-inflammatory pathway. Also provided is a method of modifying inflammatory reactions in microglia and neurons by regulating a soluble Aβ pro-inflammatory pathway. A method of treating patients with vascular disease by modifying an intracellular soluble Aβ pro-inflammatory pathway is also provided. A pharmaceutical composition consisting essentially of an effective amount of a soluble Aβ pro-inflammatory pathway regulator in a pharmaceutically effective carrier is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.