Patent · US Active

Manufacture of a chromatography matrix

US7608187B2 · kind B2 · utility

1Cited by
9References
17Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 16, 2006
Grant dateOct 27, 2009
Priority date
Expiry dateNov 16, 2026

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01J39/26
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

The present invention relates to method of manufacturing a sulphonate-functionalized (S-functionalized) cation exchanger, which method comprises reacting olefinic groups with bisulphite in the presence of at least one amine oxide, such as N-methyl morpholine oxide (NMO). The olefinic groups of the carrier may be allyl groups; which may be provided on extenders such as polyhydroxyfunctional polymers. In one embodiment, the carrier is made of agarose with improved flow pressure properties.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.