Gene regulation in transgenic animals using a transposon-based vector

US7608451B2 · kind B2 · utility

Assignees

• TransGenRx, Inc. · US
• The Board of Supervisors of Louisiana State University and Mechanical College · US

Inventors

• Richard K. Cooper · Baton Rouge, US
• Gary Cadd · Grapevine, US
• William C. Fioretti · Colleyville, US
• Kenneth F. De Boer · Ryegate, US

Key dates

• Filing date: Oct 31, 2007
• Grant date: Oct 27, 2009
• Expiry date: Oct 31, 2027

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Administration of modified transposon-based vectors has been used to achieve stable incorporation of exogenous genes into animals. These transgenic animals produce transgenic progeny. Further, these transgenic animals produce large quantities of desired molecules encoded by the transgene. Transgenic egg-laying animals produce large quantities of desired molecules encoded by the transgene and deposit these molecules in the egg.