Soluble low-density lipoprotein receptor related protein binds directly to Alzheimer's amyloid-beta peptide
US7608586B2 · kind B2 · utility
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Key dates
| Filing date | Jun 14, 2004 |
| Grant date | Oct 27, 2009 |
| Priority date | — |
| Expiry date | Jun 14, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/2821
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A soluble derivative of low-density lipoprotein receptor related protein-1 (sLRP-1) binds directly to Alzheimer's amyloid-β peptide (Aβ). This binding may be used to detect Aβ or to separate Aβ from the rest of a subject's body. In Alzheimer's disease, it may be used to provide diagnostic results by detecting Aβ, treatment by removing Aβ, or both.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.