Patent · US Expired

Hsp90 inhibitors, methods of making and uses therefor

US7608611B2 · kind B2 · utility

1Cited by
4References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 31, 2005
Grant dateOct 27, 2009
Priority date
Expiry dateJan 8, 2026

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention provides purified 18,21-didehydro-18,21-dideoxo-18,21-dihydroxy-geldanamycin derivatives, pharmaceutically acceptable salts thereof and prodrugs thereof that are potent Hsp90 binding agents that are useful for the treatment and/or the amelioration of symptoms of cancer and other proliferative tissue disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.