Oligonucleotides, agents containing these oligonucleotides, and the use thereof

US7608705B2 · kind B2 · utility

Assignee

• UNIVERSITATSKLINIKUM SCHLESWIG-HOLSTEIN · DE

Inventors

• Ernst Bayer
• Thomas Ketterer · Bingen, DE
• Holger Kalthoff · Kiel, DE
• Hendrik Ungefroren · Hamburg, DE
• Michael Gerster · Birkenfeld, DE
• Alexander Fiedler · Bonn, DE

Key dates

• Filing date: Sep 28, 2001
• Grant date: Oct 27, 2009
• Expiry date: Mar 6, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2310/3515
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to particular oligonucleotides, pharmaceutical agents that contain these oligonucleotides, and to the therapeutic use thereof. The oligonucleotides are, in particular, capable of inhibiting the proliferation of pancreatic tumors. These oligonucleotides thus have a therapeutic potential for the treatment of pancreatic tumors. This can involve, in the broadest sense, an antisense therapy.