Gastrointestinal bioreactor
US7611480B2 · kind B2 · utility
Inventor
Key dates
| Filing date | Apr 24, 2003 |
| Grant date | Nov 3, 2009 |
| Priority date | — |
| Expiry date | Feb 3, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2210/1042
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An in-vivo bioreactor device producing a dialysis effect by acting within the gastrointestinal tract for the removal of undesirable concentrated intestinal or blood substances or metabolites is disclosed. The ingestible device is comprised of a body wall that surrounds an internal compartment. Along the wall of the shell are openings located around the periphery that allow bodily fluids to enter and exit device. The wall of the device is comprised in whole or at least in part of materials that are impermeable to the passage of external fluids and maintains its physical and chemical integrity in the environment of use during its activity. Semi-permeable membranes located either internally or externally of the device are able to withstand all physiological temperatures and pH and act in a similar manner to dialysis membranes that are used for the separation of substances in suspensions, solutions, tissue cultures, etc. Treatment materials, including fixing agents that act in a similar manner to ion exchange resins, biologically active agents including proteins, enzymes, or live bacteria, and medicinal agents, can be placed in the internal cavity of the device for the treatment of var…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.