Mesostructured silica/block copolymer monoliths as a controlled release device and methods of manufacture
US7611731B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 12, 2005 |
| Grant date | Nov 3, 2009 |
| Priority date | — |
| Expiry date | Feb 1, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2031
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention comprises the design, synthesis, and characterization of mesostructured silica/block copolymer composite monoliths as controlled release systems. The controlled release function is based on the formation of mesostructured silica/block copolymer architectures via surfactant-templated sol-gel processing. Multi-layered or gradient monoliths are produced by layer-by-layer sol-gel processing to provide pulsed and programmed release characteristics. A simple, rapid route to prepare combinatorial compositional monolith libraries provides high-throughput synthesis and rapid screening of the release characteristics of the monoliths.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.