Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US7611831B2 · kind B2 · utility
18Cited by
84References
56Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 4, 2005 |
| Grant date | Nov 3, 2009 |
| Priority date | — |
| Expiry date | May 20, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2202/22
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and devices are provided for reducing the concentration of low molecular weight compounds in a biological composition containing cells while substantially maintaining a desired biological activity of the biological composition. The device comprises highly porous adsorbent particles, and the adsorbent particles are immobilized by an inert matrix. The matrix containing the particles is contained in a housing, and the particles range in diameter from about 100 μm to about 1500 μm. The device can be used to adsorb and remove a pathogen-inactivating compounds from a biological composition such as a blood product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.