Patent · US Active

Enzymatic ammonolysis process for the preparation of intermediates for DPP IV inhibitors

US7611880B2 · kind B2 · utility

0Cited by

2References

15Claims

0Family size

Assignee

Bristol-Myers Squibb Company · US

Inventors

Ramesh N. Patel · Bound Brook, US
Ronald L. Hanson · Morristown, US
Iqbal Gill · Denville, US
David B. Brzozowski · Piscataway, US
Paul M. Skonezny · Baldwinsville, US
Michael Politino · Syracuse, US
Jason G. Chen · Manlius, US
Francisco Moris-Varas · Chicago, US
Brenda J. White · Jamesville, US

Key dates

Filing date	Apr 18, 2007
Grant date	Nov 3, 2009
Priority date	—
Expiry date	Jan 23, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P17/12
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

An enzymatic ammonolysis process is provided for the preparation of intermediates used in preparing dipeptidyl peptidase IV inhibitors wherein the enzyme Candida antarctica lipase-B is used to catalyze the ammonolysis process.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.