Dibenzo[b,f]oxepine-10-carboxamides and pharmaceutical uses thereof

US7612054B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Yves Auberson · Allschwil, CH
• Claudia Betschart · Basel, CH
• Stefanie Flohr · Basel, CH
• Ralf Glatthar · Annaberg-Buchholz, DE
• Oliver Simic · Basel, CH
• Marina Tintelnot-Blomley · Maulburg, DE
• Thomas J. Troxler · Wahlen, CH
• Eric Vangrevelinghe · Saint-Louis, FR
• Siem Jacob Veenstra · Basel, CH

Key dates

• Filing date: Jul 23, 2004
• Grant date: Nov 3, 2009
• Expiry date: Jul 23, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2603/32
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention pertains to novel dibenzo[b,f]oxepine-10-carboxamides compound to a process for the preparation of such compounds of formula I, their use as a pharmaceuticals, especially in the treatment of neurological and vascular disorders related to beta-amyloid generation and/or aggregation, and to pharmaceutical compositions and combinations comprising such compounds of formula I.