Patent · US Active

Heterocyclic compounds as inhibitors of beta-lactamases

US7612087B2 · kind B2 · utility

75Cited by
4References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 26, 2004
Grant dateNov 3, 2009
Priority date
Expiry dateJul 13, 2026

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention discloses and claims methods for inhibiting bacterial β-lactamases and treating bacterial infections by inhibiting bacterial β-lactamases in man or an animal comprising administering a therapeutically effective amount to said man or said animal of a compound, or pharmaceutically acceptable salt thereof, of formula (I) either alone or in combination with a β-lactamine antibiotic wherein said combination can be administered separately, together or spaced out over time. Pharmaceutical compositions comprising a compound of formula (I), or a combination of a compound of formula (I) and a therapeutically effective amount of a β-lactamine antibiotic, and a pharmaceutically acceptable carrier are also disclosed and claimed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.