Tetrahydroisoquinolines as factor Xa inhibitors
US7612089B2 · kind B2 · utility
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2References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 21, 2005 |
| Grant date | Nov 3, 2009 |
| Priority date | — |
| Expiry date | Oct 3, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds represented by Formula I and pharmaceutically acceptable salts, solvates, hydrates, and prodrugs thereof which are inhibitors of Factor Xa. The present invention is also directed to and intermediates used in making such compounds, pharmaceutical compositions containing such compounds, methods to prevent or treat a number of conditions characterized by undesired thrombosis and methods of inhibiting the coagulation of a blood sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.