Compositions and methods for producing recombinant proteins
US7612186B2 · kind B2 · utility
1Cited by
15References
73Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 22, 2005 |
| Grant date | Nov 3, 2009 |
| Priority date | — |
| Expiry date | Jul 28, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/03
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A class of integral membrane proteins, referred to as Mistic polypeptides, their variants, fusion proteins including a Mistic polypeptide domain, and nucleic acid molecules encoding Mistic polypeptides and Mistic fusion proteins are disclosed herein. Also described are methods of using Mistic polypeptides and Mistic fusion proteins to produce and/or isolate recombinant proteins (including without limitation classes of eukaryotic proteins that have previously been intractable to recombinant bacterial expression, such as, eukaryotic integral membrane proteins).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.