Patent · US Active

Inhibitors of protein kinases

US7612200B2 · kind B2 · utility

2Cited by
20References
1Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 7, 2005
Grant dateNov 3, 2009
Priority date
Expiry dateJan 19, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention is directed to a compound having the formulawherein R1, R2, R3, R4, G, and Q are defined herein. The compounds of the present invention are useful as inhibitors of protein kinases. The present invention is also directed to compositions comprising a compound according to the above formula. The present invention is also directed to compounds that stabilize the open conformation of a protein kinase, a crystallized protein kinase in the open conformation, and uses thereof. The compounds and compositions described herein are useful for treating and preventing an inflammatory condition or disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.