Flow-through microfluidic nuclear magnetic resonance(=NMR)-chip
US7612563B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 3, 2007 |
| Grant date | Nov 3, 2009 |
| Priority date | — |
| Expiry date | Oct 12, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/307
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A flow-through microfluidic NMR-chip comprising a substrate (5) which is planar in an yz-plane with a sample chamber (2) within the substrate (5), the sample chamber (2) being elongated and having walls which run parallel to the z-direction, the substrate (5) having a thickness in x-direction of a Cartesian xyz-coordinate system between 100 μm and 2 mm, and at least one planar receiving and/or transmission coil (1, 1′) with conductor sections (11) the coil (1, 1′) being arranged at least on one planar surface of the substrate (5), wherein the extension of the sample chamber (2) along the z-direction exceeds the extension of the coil (1) along the z-direction is characterized in that the extension of the coil (1, 1′) along the z-direction is larger than its extension along the y-direction. The inventive NMR-chip facilitated NMR-spectroscopic measurements with improved resolution, sensitivity as well as B1 homogeneity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.