Apparatus and methods for compensation of blood volume effects on NIR spectroscopic measurements of blood analytes
US7613488B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 22, 2003 |
| Grant date | Nov 3, 2009 |
| Priority date | — |
| Expiry date | Aug 22, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2560/0252
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The present invention provides a method for measuring a blood analyte concentration of a body part comprising removing a portion or all of the blood from the body part to produce a modified body part, and recording a first absorbance value of the modified body part. This is followed by filling the body part with blood to produce a filled body part, and recording a second absorbance value of the filled body part. A difference spectrum is obtained by subtracting the first absorbance values from the second absorbance values, and a calibration algorithm for the blood analyte is applied to the difference spectrum, thereby measuring the concentration of the blood analyte. Also provided is an apparatus for determining the concentration of a blood analyte of a body part. The apparatus comprising a chamber of a size and shape to receive the body part, where the chamber comprises an element for withdrawing and reintroducing blood from the body part, when the body part is inserted within the chamber. The chamber also comprising one or more than one port for introducing electromagnetic radiation into the chamber and onto that body part, and collecting remaining electromagnetic radiation follow…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.