Patent · US Active

Methods for treating a subject having cancer by the administration of a conjugate between a variant staphylococcal entertoxin E superantigen and an antibody that binds to the 5T4 antigen

US7615225B2 · kind B2 · utility

50Cited by

25References

51Claims

0Family size

Assignee

Active Biotech AB · SE

Inventors

Goran Forsberg · Karlstad, SE
Eva Erlandsson · Dalby, SE
Per Antonsson · Malmö, SE
Björn Walse · Lund, SE

Key dates

Filing date	Sep 25, 2006
Grant date	Nov 10, 2009
Priority date	—
Expiry date	Nov 13, 2027

Classification

Technology area (CPC H)Electricity
CPC primaryH04L51/58
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to compositions and methods of use, wherein the composition comprises a conjugate of a bacterial superantigen and an antibody moiety. More particularly, the bacterial superantigen has been modified to decrease seroreactivity with retained superantigen activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.