Antithrombotic ethers

US7615568B2 · kind B2 · utility

Assignee

• ELI LILLY AND COMPANY · US

Inventors

• Jeffry Bernard Franciskovich · Zionsville, US
• David Kent Herron · Indianapolis, US
• Jared Harris Linebarger · Indianapolis, US
• Angela Lynn Marquart · Greenwood, US
• John Joseph Masters · Fishers, US
• David Mendel · Indianapolis, US
• Leander Merritt · Indianapolis, US
• Andrew Michael Ratz · Greenwood, US
• Gerald Floyd Smith · Indianapolis, US
• Leland O. Weigel · Indianapolis, US
• Michael Robert Wiley · Zionsville, US
• Ying Kwong Yee · Kennett Square, US

Key dates

• Filing date: Apr 13, 2004
• Grant date: Nov 10, 2009
• Expiry date: Nov 6, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This application relates to a compound of formula I (or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug thereof) as defined herein, pharmaceutical compositions thereof, and its use as an inhibitor of factor Xa and/or thrombin, as well as a process for its preparation and intermediates therefor (I).