1-pyridyl-benzofuro[3,2-b]pyridin-2(1H)-ones

US7615639B2 · kind B2 · utility

Assignee

• Tibotec Pharmaceuticals Ltd. · IE

Inventors

• Bart Rudolf Romanie Kesteleyn · Berlare, BE
• Pierre Jean-Marie Bernard Raboisson · Sligo, IE
• Dominique Louis Nestor Surleraux · Braine-le-Comte, BE
• Geerwin Yvonne Paul Haché · Brasschaat, BE
• Sandrine Marie Helene Vendeville · Woluwe-Saint-Pierre - Sint-Pieters-Woluwe, BE
• Piet Tom Bert Paul Wigerinck · Terhagen, BE
• Annick Ann Peeters · Wilrijk, BE

Key dates

• Filing date: May 17, 2005
• Grant date: Nov 10, 2009
• Expiry date: May 29, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P31/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

1-heterocyclyl-1,5-dihydro-pyrido[3,2-b]indol-2-ones of formula (I):the N-oxides, salts, stereoisomeric forms, racemic mixtures, prodrugs, esters and metabolites thereof, wherein n is 1, 2 or 3; —CpH2p—CH(OR14)—CqH2q—R15   (b-3);—CH2—CH2—(O—CH2—CH2)m—OR14   (b-4);—CH2—CH2—(O—CH2—CH2)m—NR5aR5b (b-5);