Materials and methods for identifying genes and/or agents that alter replicative lifespan
US7618774B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Mar 1, 2004 |
| Grant date | Nov 17, 2009 |
| Priority date | — |
| Expiry date | Sep 8, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/39
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Recombinant materials, including DNA constructs, expression vectors, and host cells, and methods of identifying an environmental stimulus or a gene that alters the lifespan of an organism are identified. The recombinant DNA constructs include first and second chimeric genes that both encode substantially the same protein that is required for yeast replication, the first chimeric gene containing a promoter responsive to growth medium conditions and the second chimeric gene containing a promoter operable in mother cells but not daughter cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.