Apparatus for electrophoretic in situ tissue staining
US7618807B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 28, 2007 |
| Grant date | Nov 17, 2009 |
| Priority date | — |
| Expiry date | Jun 19, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/325
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention introduces a radically different way of accelerating biomolecule conjugates into tissue, and hence towards their targets for purposes of tissue staining. The invention provides for an order of magnitude improvement over the prior art diffusion process used to stain tissue. The invention comprises a method of tissue staining by applying an electric field to a tissue sample in the presence of an electrolyte and biomolecular conjugates of interest suspended in the electrolyte. Typical staining times are reduced to seconds as opposed to 30-120 minutes common in the prior art. The invention is also directed to devices for performing the method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.