Process for producing optically active compound
US7619003B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 28, 2004 |
| Grant date | Nov 17, 2009 |
| Priority date | — |
| Expiry date | Mar 15, 2025 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2531/845
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A process for producing an optically active compound based on the hydrolysis of an alkenyl ester compound or the cleavage of an alkenyl ether compound. The process uses neither an acidic compound nor a basic compound, and reactants can be reacted in a high concentration. It does not necessitate a buffer, nutrient, etc. unlike enzymatic reactions or reactions using a microorganism. It is a simple process which attains a satisfactory production efficiency. The process, which is for producing an optically active carboxylic acid or optically active alcohol represented by the general formula (VI): (wherein R1, R2, and R3 are different groups; and A represents methylene, carbonyl, or a single bond), is characterized by causing water to act on an alkenyl ester or alkenyl ether represented by the general formula (I): (wherein R4, R5, and R6 each represents hydrogen, alkyl, etc.) in the presence of a specific transition metal complex having an optically active ligand.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.