Epitope/peptide recognized by HLA-A2402-restricted Ep-CAM-specific CTL and use of the same
US7619058B2 · kind B2 · utility
Assignees
Inventor
Key dates
| Filing date | Jan 19, 2005 |
| Grant date | Nov 17, 2009 |
| Priority date | — |
| Expiry date | Apr 11, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A peptide consisting essentially of the amino acid sequence represented by SEQ ID NO:1; a peptide consisting essentially of the amino acid sequence represented by SEQ ID NO:2; or a mutant peptide consisting essentially of an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO:1 or 2 by addition, deletion or substitution of one or more amino acids, the peptide being capable of forming a complex with an HLA-A2402 molecule to be recognized by HLA-A2402-restricted cytotoxic T lymphocytes or induce such lymphocytes. Such a peptide is useful as a cancer vaccine for epithelial cancer patients having HLA-A2402.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.