Process for the preparation of 3-spiro′cyclohexan-1,3′-′3H!indolin-2′-one! derivatives
US7619082B2 · kind B2 · utility
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3References
18Claims
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Assignee
Inventors
Key dates
| Filing date | Jul 25, 2002 |
| Grant date | Nov 17, 2009 |
| Priority date | — |
| Expiry date | Dec 30, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparation of a compound of the formula (I) by reacting a compound of the formula (II) with a compound of the formula (III) characterized by dissolving the compounds of the formula (II) and formula (III) in a water-inmiscible organic solvent in the presence of a phase transfer catalyst, reacting with a.) an aqeuos solution of a base, or b.) a base in solid form directly and if desired transforming the compound of formula (I) thus obtained into its salt.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.