Antagonists of the vanilloid receptor subtype 1 (VR1) and uses thereof
US7622493B2 · kind B2 · utility
5Cited by
1References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 13, 2007 |
| Grant date | Nov 24, 2009 |
| Priority date | — |
| Expiry date | Jun 2, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D493/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds of formula (I)wherein variables X1, X2, Y, R1a, R1b, R2a, R2b, A1, A2, A3, and A4 are as defined in the description, and methods of use to treat pain, neuropathic pain, allodynia, pain associated with inflammation or an inflammatory disease, inflammatory hyperalgesia, bladder overactivity, and urinary incontinence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.