Patent · US Expired

Antibodies which are directed against the Marburg I polymorphism of factor VII-activating protease (FSAP), and their preparation and use

US7622558B2 · kind B2 · utility

1Cited by

8References

10Claims

0Family size

Assignee

Siemens Healthcare Diagnostics Products GmbH · DE

Inventors

Herbert Schwarz · Niedereschach, DE
Harald Althaus · Wetter, DE
Bodo Fischer · Marburg, DE
Thomas Wissel · Marburg, DE

Key dates

Filing date	Aug 23, 2005
Grant date	Nov 24, 2009
Priority date	—
Expiry date	Nov 29, 2025

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/806
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to antibodies which are directed against the FSAP Marburg I variant and to their preparation and use, in particular in therapy and diagnosis. The antibodies are characterized by the fact that they bind specifically to the FSAP MR I variant but not to the FSAP wild-type protein or other mutant variants which are characterized by amino acid substitutions at other positions in the FSAP protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.