Antibacterial agents and methods of identifying and utilizing same
US7625707B2 · kind B2 · utility
0Cited by
77References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 27, 2004 |
| Grant date | Dec 1, 2009 |
| Priority date | — |
| Expiry date | Aug 17, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of identifying a molecule capable of inducing death of a bacterial cell which includes exposing toxin and antitoxin polypeptides of a toxin-antitoxin pair produced by the bacterial cell to a plurality of molecules, and identifying a molecule of the plurality of molecules capable of preventing or disrupting binding between the antitoxin and said toxin polypeptides, thereby identifying the molecule capable of inducing death of the bacterial cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.