Sutstituted tetrahydropyrrolopyrazine compounds and the use thereof in the treatment and/or inhibition of pain

US7625900B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Beatrix Merla · Aachen, DE
• Thomas Christoph · Aachen, DE
• Stefan Oberboersch · Aachen, DE
• Klaus Schiene · Goldkronach, DE
• Gregor Bahrenberg · Monschau, DE
• Robert Frank · Aachen, DE
• Sven Kuehnert · Lehrte, DE
• Wolfgang Schroeder · Aachen, DE

Key dates

• Filing date: Oct 17, 2007
• Grant date: Dec 1, 2009
• Expiry date: Oct 17, 2027

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P29/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted tetrahydropyrrolopyrazine compounds corresponding to the formula I:processes for their preparation, pharmaceutical compositions comprising these compounds and the use of these compounds for the treatment and/or inhibition of pain and other disorders or disease states at least partly mediated by KCNQ2/3 K+ channels.