Patent · US Active

Synthesis of himbacine analogs

US7626045B2 · kind B2 · utility

3Cited by
5References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 23, 2009
Grant dateDec 1, 2009
Priority date
Expiry dateApr 23, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D405/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to an improved process for preparing himbacine analogs. The compounds are useful as thrombin receptor antagonists. The improved process may allow for at least one of easier purification by crystallization, easier scalability, and improved process yield on the desired enantiomer.An example of a step in the synthesis of such a himbacine analog is as follows:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.