Evolution of whole cells and organisms by recursive sequence recombination
US7629170B2 · kind B2 · utility
161Cited by
87References
33Claims
0Family size
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Key dates
| Filing date | Aug 17, 2006 |
| Grant date | Dec 8, 2009 |
| Priority date | — |
| Expiry date | Mar 28, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/465
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.