Substituted monocyclic CGRP receptor antagonists
US7629338B2 · kind B2 · utility
21Cited by
13References
41Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 7, 2007 |
| Grant date | Dec 8, 2009 |
| Priority date | — |
| Expiry date | Jan 22, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D519/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of formula I:(wherein variables A1, A2, A3, A4, m, n, J, Q, R4, Ea, Eb, Ec, R6, R7, Re, Rf, RPG and Y are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.