3-(imidazolyl)-pyrazolo[3,4-b]pyridines
US7629344B2 · kind B2 · utility
9Cited by
5References
6Claims
0Family size
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Key dates
| Filing date | May 21, 2008 |
| Grant date | Dec 8, 2009 |
| Priority date | — |
| Expiry date | May 21, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are 3-imidazoyl-pyrazolo[3,4-b]pyridine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.